Pneumonia

Vopr Kurortol Fizioter Lech Fiz Kult. 2016 Mar-Apr;93(2):9-12.

The influence of low-intensity laser radiation on the functional activity of neutrophils in the patients presenting with community-acquired pneumonia.

[Article in Russian]
Burduli NM1, Gabueva AA1.

Author information

  • 1State budgetary educational institution of higher professional education ‘North-Ossetian State Medical Academy’, Russian Federation Ministry of Health, Republic of North Ossetia – Alania, Vladikavkaz, Russia.

Abstract

in English, Russian

AIM:

The objective of the present study was to elucidate the influence of low-intensity laser radiation on the results of the nitroblue tetrazolium (NBT) test in the patients presenting with community-acquired pneumonia.

PATIENTS AND METHODS:

A total of 100 patients with community-acquired pneumonia were available for the examination of whom 70 were treated with intravenous low-intensity laser irradiation of blood (ILIB) by means of the ILIB-405 technique during 7 days. The functional activity of neutrophils was estimated from their ability to reduce nitroblue tetrazolium in both spontaneous and stimulated NBT-tests.

RESULTS:

The analysis of the data obtained in the study has demonstrated the significant improvement of the results of the NBT tests in the group of patients receiving the ILIB treatments regardless of whether its content was originally elevated or reduced.

CONCLUSION:

The inclusion of intravenous low-intensity laser irradiation of blood in the combined treatment of the patients with community-acquired pneumonia appreciably promotes normalization of the bactericidal activity of neutrophils.

Vopr Kurortol Fizioter Lech Fiz Kult. 2015 Mar-Apr;92(2):9-11.

The influence of low-intensity laser irradiation of blood on the lactoferrin level in the patients presenting with community-acquired pneumonia.

[Article in Russian]
Gabueva AA, Burduli NM.

Abstract

The objective of the present study was to estimate the influence of low-intensity laser irradiation of blood on the levels of lactoferrin in the patients presenting with community-acquired pneumonia.

MATERIALS AND METHODS:

All the patients were divided into two groups. Those comprising the control group received only medicamental therapy. The standard treatment of the patients in the second group was supplemented by intravenous laser irradiation of blood (IVLIB-405 technique). Each irradiation session performed in a continuous mode lasted 5-7 minutes, with the total treatment course consisting of 7 daily procedures. Lactoferrin was determined before and after the treatment by the enzyme immunoassay with the use of “Lactoferrin Strip” kits (“Vektor-Best- Yug” JSC, Russia).

RESULTS:

Analysis of the results of the study revealed a significant decrease in the blood lactoferrin level down to the normal range in the patients treated with the use of laser therapy.

CONCLUSION:

The application of intravenous laser irradiation of blood for the combined treatment of the patients with community-acquired pneumonia was accompanied by normalization of the blood lactoferrin level and the improvement of the clinical course of the disease.

Ter Arkh. 2010;82(3):36-8.

Changes in plasma hemostatic parameters under intravascular laser irradiation of blood in patients with community-acquired pneumonia.

[Article in Russian]

Burduli NM, Pilieva NG.

Abstract

AIM: To study the time course of changes in the activity of the protein C system and other hemostatic parameters under intravascular laser irradiation of blood (ILIB) in patients with community-acquired pneumonia (CAP).

SUBJECTS AND METHODS: One hundred and forty patients aged 17 to 62 years (mean 39.5 +/- 8.4 years) with CAP were examined. A control group (n = 40) received conventional drug therapy; the study group (n = 100) had a course of ILIB in addition to conventional therapy.

RESULTS: Before treatment, the patients with CAP were observed to have a lower protein C system activity and the signs of hypercoagulation that were eliminated by ILIB.

CONCLUSION: ILIB is an effective method in correcting hemocoagulative disorders in patients with CAP.

Klin Med (Mosk). 2007;85(7):48-50.

The dynamics of microcirculation parameters in patients with pneumonia receiving intravenouls irradiation of blood as a part of complex treatment.

[Article in Russian]

Burduli NM, Pilieva NG.

The aim of the study was to evaluate the condition of the microcirculatation under the influence of low-intensity laser irradiation as a part of complex treatment of patients with pneumonia. The subjects were 62 patients with pneumonia divided into two groups. The 30 patients of the control group received only conventional medication therapy, while the 32 patients of the main group received a course of laser irradiation of blood (LIB) in addition to conventional medication. Positive dynamics in microcirculation was more prominent in the main group. In conclusion, LIB may be considered to be an effective method to correct microcirculatory disturbances in patients with pneumonia.

Vestn Ross Akad Med Nauk. 2005;(9):20-6.

Intracavitary laser therapy and its effect on the kallikrein-kinin system of blood in children with pneumothorax.

[Article in Russian]

Tsuman VG, Mashkov AE, Shcherbina VI, Surovkina MS, Sinenkova NV.

The article presents the results of low-intensity laser application in complex treatment of 137 children with acute purulent destructive pneumonia complicated by pneumothorax with bronchial fistulas. A method of intracavitary laser therapy, developed in the clinic, allowed obliteration of bronchopleural fistulas without application of bronchial occlusion and other invasive techniques. Evaluation of the kallikrein-kinin system of blood revealed prominent reduction of kininogenesis in most (87%) patients upon admission (3 weeks after the onset of the disease), which is an important link of the pathogenesis of late stages of complicated acute purulent lung destruction in children. The study also demonstrated that low-intensity laser emission modulates pyoinflammatory process due to its effect on cell-mediated immunity, neutrophilic phagocytosis and the kallikrein-kinin system of blood. Intracavitary laser therapy is the treatment of choice in children with acute purulent destructive pneumonia complicated by pneumothorax with bronchial fistulas. Application of intracavitary laser therapy in complex therapy of complicated acute purulent lung destruction in children allowed discharge from the hospital 5 to 7 day earlier, and prevented lung inflammatory process chronization. None of the patients have died within last 10 years.

Lik Sprava. 2002 Jul-Sep;(5-6):36-9.

Degree of endogenous intoxication in children with acute pneumonia in the presence of hypotrophy.

[Article in Ukrainian]

Gafarova FM, Abduzhabbarova ZM.

Children with acute pneumonia in the presence of hypotrophy derive no benefit from conventional therapy, with no change for the better being noted in the degree of endogenous intoxication. Endotoxemia has been shown to be alleviated by endovascular laser irradiation of blood included in the complex of therapeutic means of remediation used in acute pneumonia against the background of hypotrophy, which fact permits reducing the volume of medicamentous therapy. The above treatment option has also been found to exert a beneficial effect on the course of the illness.

Ter Arkh. 2002;74(3):40-3.

 

Parameters of membrane permeability, microcirculation, external respiration, and trace element levels in the drug-laser treatment of pneumonia.

[Article in Russian]

Amirov NB.

AIM: To study effects of laser therapy in combined treatment of pneumonia on external respiration function, membrane permeability, microcirculation and serum trace elements. MATERIAL AND METHODS: 142 pneumonia patients were randomly divided into two groups: 96 patients treated with drugs and laser radiation (the study group) and 46 patients treated with drugs only (control group). RESULTS: In the study group there was more pronounced reduction in cell membrane permeability, a rise in concentrations of iron and chromium in the blood serum, improvement of microcirculation. These changes closely correlated with those in immunity, external respiration function. CONCLUSION: Laser therapy is an effective method of pneumonia treatment and can be included in relevant combined schemes.

Vopr Kurortol Fizioter Lech Fiz Kult. 2001 May-Jun;(3):15-8.

 

Laser therapy of elderly patients with pneumonia

[Article in Russian]

Lutai AV, Egorova LA, Shutemova EA.

The aim of the study was to evaluate the efficiency of laser therapy included into the treatment of pneumonia in the elderly. A follow-up included the analysis of their clinical status and external respiratory function, pulmonary blood flow, and immunological parameters in 2 matched groups of pneumonia patients aged 60 to 72 years. Low-intensity laser therapy (transcutaneous sliding contact procedure) was used as part of routine treatment in one of the groups. The findings demonstrate that non-drug treatment had an undeniably positive impact. There was an earlier regress of clinical symptoms and a sound recovery of functional parameters. In the absence of side effects of this method, these data allow infrared laser therapy to be recommended for rehabilitation of elderly patients with pneumonia.

LOV-LEVEL LASER THERAPY IN PATIENTS WITH PNEUMONIA

Kustova N.L., Yemelyanova L.A.

Urals State Medical Academy, Yekaterinburg, Russia

We compared the effectiveness of complex treatment including transcutaneous low-level laser radiation of chest by He-Ne laser /66 patients/, AsGa laser/68 patients/, magnet-laser therapy/66 patients/ and decimeter-wave therapy /62 patients/. We used individual laser radiation dosing method according to V.M. Lisienko and R.I Mintz / 1987/. All three types of laser therapy have beneficial influence on inflammation proc-ess in patients with pneumonia, having positive effects on laboratory and rentge-nological symptoms. After such treatment patients recover two times faster, especially after infrared laser radiation or its combination with magnettherapy. Structural optical serum properties evaluation with the help of polarization microscopy and refractome-try methods showed that there are many liquid crystals of different types in the begin-ning of pneumonia. There is feedback between serum refraction index and severity of pneumonia, existence of complications. After treatment serum refraction index aver-age values returned to normal in all four groups of patients. Laser therapy improves immune status of patients. Magnct-lasertherapy and infra-red laser radiation are the most effective, including cases of lingering disease. Individual laser radiation dosage stimulates phagocytosis. According to the above-mentioned complex treatment of pneumonia can include low-level laser radiation.

Vopr Kurortol Fizioter Lech Fiz Kult. 1995 May-Jun;(3):12-4.

 

An evaluation of the effect of magnetic-laser therapy on external respiratory function in complicated forms of acute pneumonia in children.

[Article in Russian]

Gaidashev EA, Lebedev KN, Khristoforov VN, Biriukov VV, Gatkin EIa.

The authors studied the effects of magnetic laser therapy (MLT) on external respiration, blood transport of gas and clinical course of acute destructive pneumonia in children aged 1-12 years. It was established that energy of infrared laser combined with magnetic field reduces the severity of acute respiratory insufficiency, treatment course, prevents destructive complications in children with infiltrative acute destructive pneumonia.

Sov Med. 1989;(7):22-6.

 

Intravenous laser therapy in multimodal treatment of acute pneumonia

[Article in Russian]

Korochkin IM, Platonova TK, Kapustina GM, Belov AM, Alekseeva OG.

Such therapy has been administered to 70 patients with acute pneumonias. 25 patients on traditional therapy have made up the reference group. The effects of laser therapy on the clinical picture, status of the coagulation system cellular and plasma factors, fibrinolysis, and on the blood stream at the site of the pneumonic involvement have been examined in the patients with acute pneumonias in single tests and after a course of treatment. Intravenous laser therapy has had a favourable effect on the clinical course of acute pneumonias, accelerating the terms of pneumonia resolution and promoting and earlier and more complete restoration of the blood stream and normalization of the hemostasis, in contrast to routine therapy.