Peptic Ulcers

Klin Med (Mosk). 2006;84(2):61-4.

The influence of low-intensive laser therapy on the aggregation properties of thrombocytes in patient with peptic ulcer.

[Article in Russian]

Burduli NM, Gutnova SK.

The purpose of the study was to evaluate the influence of low-intensive laser therapy (LILT) on the aggregation properties of thrombocytes in patients with exacerbation of peptic ulcer (PU). The subjects, 111 patients aged 18 to 63, were divided into two groups: the main group (n = 81), and the control group (n = 30). In addition there were 15 healthy people who also underwent examination. Patients in the main group received complex treatment with untiulcer drugs and different methods of laser therapy: intravenous laser irradiation of blood, cutaneous irradiation, and a combination of both. The control group was treated with drugs only. The study found various changes in the aggregation properties of thrombocytes in patients with PU exacerbation, which consisted mostly in hyperaggregation. LILT had a normalizing effect on the aggregation properties of thrombocytes in patients of the main group.

Vrach Delo. 1991 Jan;(1):24-7.

[Biogenic amines and cyclic nucleotides in the laser therapy of long-term nonhealing stomach ulcers]

[Article in Russian]

Loginov AS, Sokolova GN, Trubitsyna IE, Sokolova SV, Markin EP, Varvanina GG.

A study is presented of the effect of copper vapors laser therapy on the content of biogenic amines–serotonin and histamine and the state of adenylcyclase (AC) system (content of cAMP, cGMP and AC activity) at the edge of the gastric ulcer. Direct effect of laser radiation (single dose 10–15 J.) produced a significant increase of serotonin, histamine, cAMP, AC activity and an insignificant increase of cGMP. Healing of the ulcerative defect after 5–6 laser therapy sessions was followed by a reduction of the content of serotonin, increase of histamine, cAMP and AC activity. The authors discuss the biostimulating effect of laser radiation by influencing the inflammatory-proliferative processes in the epitheliocytes in prolonged nonhealing gastric ulcers.

Sov Med. 1991;(2):9-11.

Effect of laser irradiation of different intensities on the processes of healing of stomach ulcers.

[Article in Russian]

Loginov AS, Sokolova GN, Smotrova IA, Potapova VB, Markin EP, Ambartsumian RV.

Patients with stubborn peptic ulcers were exposed to copper vapor laser of various intensities with similar irradiation energy. The best therapeutic effect (more rapid ulcer healing) was achieved when ulcer bottom and edges were exposed to laser of higher intensity; the effect is explained by a higher stimulation of inflammation and a more rapid and clear-cut restructuring of connective-tissue stroma on ulcer bottom.

Klin Med (Mosk). 1991 Jul;69(7):44-7.

Low-intensity laser irradiation in the treatment of peptic ulcer

[Article in Russian]

Barakaev SB.

The course of gastric and duodenal ulcer was investigated in 120 ulcer patients exposed to low-intensity laser irradiation with 0.63 microns wave length. Compared to conventional treatment, laser therapy of ulcer has a number of advantages allowing its wide introduction in both hospital and outpatient settings. Benefits and drawbacks of endoscopic and transcutaneous laser therapy are comparatively assessed.

Ter Arkh. 1986;58(3):76-8.

Endoscopic laser therapy of stomach and duodenal ulcers

[Article in Russian]

Shishkov AS, Berlinski? VD, Kirichenko GD.

The authors analyse the results of the treatment of peptic ulcer of the stomach and duodenum by indestructible red laser radiation in 65 patients. Complete healing of ulcer was attained in 92.3% of the cases. In 7.7% of the patients, ulcer appeared resistant to laser radiation. Peptic ulcer relapsed in 6.2% of the patients. It is shown that the efficacy of laser radiation treatment is dependent on the ulcer localization.